Investigation of the triplet excited state and application of cationic meso-tetra(cisplatin)porphyrins in antimicrobial photodynamic therapy

In this manuscript, we report, the photophysical study of triplet excited states and antimicrobial photoinactivation positively charged tetra-cisplatin porphyrin derivatives against Gram + ? bacterial strains. Isomeric cisplatin-porphyrins were used applied in aPDT assays bacilli Escherichia coli, Klebsiella pneumoniae Pseudomonas aeruginosa (Gram negative) a cocci Staphylococcus aureus positive) The results show that compound substituted at meta position (3-cis-PtTPyP) is more efficient photosensitizer bacteria culture. way, tetra-cationic porphyrins containing cisplatin might be promising agents with potential applications clinical infections.